25 years of CENTIS. Pandemic and Radiopharmaceuticals
Main Article Content
Abstract
Close to its 25th anniversary, CENTIS evaluates its work in the context of the disorders triggered by COVID-19. For this purpose, the situation of nuclear medicine and radiopharmacy, before and during the epidemic and their current development prospects is examined. The production of radiopharmaceuticals continues to be a consolidated global industry and although the pandemic affects this area, the presence of other diseases does not cease, so essential and critical nuclear medicine services are still needed, therefore its gradual reopening is expected. In addition, research will be taken with more strength, given that COVID-19 is so complex and associated with so many factors that it constitutes virgin terrain in perspective for diagnostic techniques in nuclear medicine. The role of therapeutic radiopharmaceuticals in an important set of diseases, especially cancer, will also remain. As a result, the Isotope Center focus its attention under good management practices, on the consolidation of the production and distribution of radiopharmaceuticals and in the development of new products. Both aspects are mainly based on two radionuclides: Tc-99m and Y-90.
Article Details
How to Cite
Cruz Arencibia, J., Leyva Montaña, R., & Morín Zorrilla, J. (1). 25 years of CENTIS. Pandemic and Radiopharmaceuticals. Nucleus, (67). Retrieved from http://nucleus.cubaenergia.cu/index.php/nucleus/article/view/698
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Panorama Nuclear
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[29] SWACHCHHANDA S, PANKAJ N, et. al. Axumin positron emission tomography: novel agent for prostate cancer biochemical recurrence. J Clin Imaging Sci. 2019; 9: 49. doi: 10.25259/JCIS_139_2019.
[30] PETRONI D, MENICHETTI L, POLI M. Historical and radiopharmaceutical relevance of [18F] FDG. Journal of Radioanalytical and Nuclear Chemistry. 2020. https://doi.org/10.1007/s10967-020-07013-y.
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[32] KENDI AT, HALFDANARSON TR, PACKARD A, DUNDAR A, SUBRAMANIAM RM. Therapy With 177Lu-DOTATATE: clinical implementation and impact on care of patients with neuroendocrine tumors. Review. Nucl. Med. and Mol. Imaging. 2019; doi.org/10.2214/AJR.19.21123.
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[34] SOWA-STASZCZAK A, et. al. Efficacy and safety of 90Y-DOTATATE, therapy in neuroendocrine tumours. Polish Journal of Endocrinology. 2011; 62: 5.
[35] CWIKLA JB, et. al. Efficacy of radionuclide treatment DOTATATE Y-90 in patients with progressive metastatic gastroenteropancreatic neuroendocrine carcinomas (GEP-NETs): a phase II study. Annals of Oncology. 2010; 21: 787-794.
[34] SCHULTZ WA. Molecular Biology of Human Cancers. Springer Science + Business Media, Inc. 2005.
[36] HICKS RJ, JACKSON P, KONG G, WARE RE, et. al. 64Cu-SARTATE PET Imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy. J Nucl Med . 2019; 60: 777-785. doi: 10.2967/jnumed.118.217745.
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